Palladium(II) Acetate ChemBeads

Pd(OCOCH₃)₂

MFCD00012453

Palladium(II) acetate is a homogenous oxidation catalyst. It participates in the activation of alkenic and aromatic compounds towards oxidative inter- and intramolecular nucleophilic reactions. Crystals of palladium(II) acetate have a trimeric structure, having symmetry D_3h. Each of the palladium atoms in the crystals are joined to the other two by double acetate bridges. Microencapsulation of palladium(II) acetate in polyurea affords polyurea-encapsulated palladium(II) acetate. It is a versatile heterogeneous catalyst for various phosphine-free cross-coupling reactions. It participates as catalyst in the Heck coupling reaction of pthalides with different alkenes.

Application Guide for Palladium Catalyzed Cross-Coupling Reactions
Catalyst for an intramolecular coupling of aryl bromides with alcohols giving 1,3-oxazepines. Preparation of cyclic ureas via palladium-catalyzed intramolecular cyclization.

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High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

~4 wt.% loading of catalyst

100

solid

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
core: palladium
reaction type: Heck Reaction
core: palladium
reaction type: Hiyama Coupling
core: palladium
reaction type: Negishi Coupling
core: palladium
reaction type: Sonogashira Coupling
core: palladium
reaction type: Stille Coupling
core: palladium
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst

GHS05,GHS07,GHS09

Danger

H317 - H318 - H410

P261 - P272 - P273 - P280 - P302 + P352 - P305 + P351 + P338

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1A

11 - Combustible Solids

WGK 2