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Hydroxy-PEG4-t-butyl ester

产品编号:4075010
CAS NO:518044-32-1
包装规格:1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40750101 G1970
产品别名

518044-32-1

Hydroxy-PEG4-t-butyl ester

tert-Butyl-1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate

HO-PEG4-CO-OtBu

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H30O7
Molecular weight
322.39
Application【应用】
This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Other Notes【其他说明】
Recruiting cytotoxic T cells to folate-receptor-positive cancer cells

Syntheses and characterizations of novel pyrrolocoumarin probes for SNAP-tag labeling technology

High density orthogonal surface immobilization via photoactivated copper-free click chemistry
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
Assay【测定】
≥95%
form【形式】
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index【折射率】
n/D 1.4492
density
1.04746 g/mL
storage temp.【储存温度】
2-8℃
SMILES string
O=C(OC(C)(C)C)CCOCCOCCOCCOCCO
O=C(OC(C)(C)C)CCOCCOCCOCCOCCO
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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