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BocNH-PEG4-acid

产品编号:4074678
CAS NO:876345-13-0
包装规格:250 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4074678250 MG2440
40746781 G6220
产品别名

876345-13-0

BocNH-PEG4-acid

Boc-NH-PEG4-CH2COOH

2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H29NO8
Molecular weight
351.39
Application【应用】
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation
Other Notes【其他说明】
A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic Applications

A Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
form【形式】
liquid
reaction suitability
reaction type: Pegylations
reagent type: cross-linking reagent
refractive index【折射率】
n/D 1.4641
density
1.1395 g/mL
storage temp.【储存温度】
−20℃
SMILES string
OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O
OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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