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Caspase-5 Inhibitor I
| 产品编号： | 4073884 |
| 规格： | Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8. |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Caspase-5 Inhibitor I
Z-WE(OMe)HD(OMe)-FMK
基本信息
| Empirical Formula【经验(实验)分子式】 | C37H42FN7O10 |
| Molecular weight | 763.77 |
| General description【一般描述】 | A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8. A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Primary Target caspase-1, caspase-4, caspase-5, caspase-8 Reversible: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F* |
| Physical form【外形】 | Supplied as a trifluoroacetate salt. |
| Reconstitution【重悬】 | Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C. |
| Analysis Note【分析说明】 | single spot by TLC |
| Other Notes【其他说明】 | Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Rano, T., et al. 1997. Chem. Biol. 4, 149. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 1 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
