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Caspase-3 Inhibitor III-CAS 285570-60-7-Calbiochem

产品编号:4073883
规格:The Caspase-3 Inhibitor III, also referenced under CAS 285570-60-7, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
CAS NO:285570-60-7
包装规格:1 MG,5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40738831 MG1660
40738835 MG5970
产品别名

285570-60-7

Caspase-3 Inhibitor III-CAS 285570-60-7-Calbiochem

Ac-DEVD-CMK

基本信息
Empirical Formula【经验(实验)分子式】
C21H31ClN4O11
Molecular weight
550.94
General description【一般描述】
A potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases.
A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10.
Biochem/physiol Actions【生化/生理作用】
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
caspase-3, caspase-6, caspase-7, caspase-8, caspase-10
Warning【警告】
Toxicity: Standard Handling (A)
Sequence【序列】
Ac-Asp-Glu-Val-Asp-CMK
Reconstitution【重悬】
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Other Notes【其他说明】
Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197
Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
lyophilized solid
powder
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
desiccated
color【颜色】
white to off-white
solubility【溶解性】
20% acetonitrile: 1 mg/mL
shipped in【运输】
ambient
storage temp.【储存温度】
−20℃
packaging【包装】
1, 5 mg in Plastic ampoule
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 1
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