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7α,27-dihydroxycholesterol-d6
产品编号: | 4070051 |
规格: | 7α,27-dihydroxycholesterol-d6, powder |
CAS NO: | 2260669-25-6 |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
2260669-25-6
7α,27-dihydroxycholesterol-d6
基本信息
Empirical Formula【经验(实验)分子式】 | C27H40D6O3 |
Molecular weight | 424.69 |
NACRES | NA.25 |
General description【一般描述】 | 7α,27-dihydroxycholesterol (7α,27-di-OHC) is synthesized by the hydroxylation of 27-hydroxycholesterol (27-OHC). It is an oxysterol with side chains oxidized and is a structural isomer of 7α,25-dihydroxycholesterol. 7α,27-dihydroxycholesterol-d6 is a deuterated derivative of 7α,27-di-OHC. |
Application【应用】 | 7α,27-dihydroxycholesterol-d6 has been used as a deuterated internal standard in liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) for human plasma oxysterol analysis. |
Biochem/physiol Actions【生化/生理作用】 | 7α,27-dihydroxycholesterol (7α,27-di-OHC) is a ligand for Epstein-Barr virus-induced gene 2 (EBI2). 7α27-di-OHC is implicated in neurological disease, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human cerebrospinal fluid (CSF) samples. The levels of 7α,27-di-OHC decreases in lipopolysaccharide activation. |
产品性质
Assay【测定】 | >99% (TLC) |
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 700136P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700136P-1mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |