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产品别名
1715-86-2
7-dehydrodesmosterol
基本信息
Empirical Formula【经验(实验)分子式】 | C27H42O |
Molecular weight | 382.62 |
NACRES | NA.25 |
General description【一般描述】 | 7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step. |
Application【应用】 | 7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). |
Biochem/physiol Actions【生化/生理作用】 | 7-dehydrodesmosterol (7-DHD) levels are higher during fetal development and increases with aging. Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model. Reduced levels of 7-DHD is observed in shiverer and quaking disorder. |
产品性质
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 700138P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
InChI | 1S/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9-10,19,21,23-25,28H,6,8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1 |
InChI key | RUSSPKPUXDSHNC-DDPQNLDTSA-N |
packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700138P-1mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |