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Anti-Rabbit IgG (H+L), F(ab) fragment-Fluorescein antibody produced in goat
产品编号: | 4066087 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Rabbit IgG (H+L), F(ab) fragment-Fluorescein antibody produced in goat
FITC
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | fluorescein conjugate |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | secondary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | rabbit |
technique(s) | direct immunofluorescence: suitable indirect ELISA: suitable indirect immunofluorescence: suitable |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
基本信息
General description【一般描述】 | Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a γ (γ) heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as fragment antigen binding (Fab) fragments. These fragments contain the light chains paired with the VH and CH1 domains of the heavy chains. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants. |
Specificity【特异性】 | This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rabbit IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities, pepsin digestion and chromatographic separation. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Fluorescein and Anti-Goat Serum. No reaction was observed against Anti-Papain or Anti-Goat IgG F(c). |
Immunogen【免疫原】 | Rabbit IgG whole molecule |
Physical properties【物理属性】 | Antibody format: IgG Fab |
Physical form【外形】 | Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free |
Reconstitution【重悬】 | Reconstitute with 1.0 mL deionized water (or equivalent). |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Pictograms【象形图】 | GHS06,GHS09 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H302 - H311 - H411 |
Precautionary Statements | P280 - P301 + P312 + P330 - P302 + P352 + P312 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 |
Supp Hazards【补充剂危害】 | EUH032 |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |