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22(R)-hydroxycholesterol-d7
产品编号: | 4064564 |
规格: | cholest-5-ene-3β,22(R)-diol-d7, powder |
CAS NO: | 1246302-93-1 |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
1246302-93-1
22(R)-hydroxycholesterol-d7
25,26,26,26,27,27,27-heptadeuterocholest-5-ene-3β,22R-diol
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C27H39O2D7 |
Molecular weight | 409.70 |
NACRES | NA.25 |
General description【一般描述】 | 22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in the neonate brain. 22(R)-hydroxycholesterol-d7 is a deuterated form of 22(R)-hydroxycholesterol. |
Biochem/physiol Actions【生化/生理作用】 | 22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimer′s disease and may be implicated in neuroinflammation and neurodegenerative diseases. |
产品性质
Assay【测定】 | >99% (TLC) |
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 700052P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700052P-1mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |