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Anti-phospho-Elk-1 (pSer383) antibody produced in rabbit
产品编号: | 4063512 |
规格: | affinity isolated antibody, buffered aqueous glycerol solution |
包装规格: | 0.1 ML |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD01092332 |
NACRES | NA.41 |
Specificity【特异性】 | The antibody detects Elk-1 protein only when phosphorylated at Ser383. |
Immunogen【免疫原】 | synthetic phosphopeptide corresponding to residues around phosphorylated Ser383 of human Elk-1. |
Application【应用】 | Anti-phospho-Elk-1 (pSer383) antibody produced in rabbit is suitable for western blotting (chemiluminescent) at a dilution of 1:1,000 using Elk-1 fusion protein phosphorylated with purified Erk2. |
Biochem/physiol Actions【生化/生理作用】 | ETS domain-containing protein Elk-1 is a protein encoded by the ELK1 gene in humans. It is a member of the Ets family of transcription factors. Elk-1 activation is important for executing its physiologic functions. Its activation is positively associated with ER and with Cyclin D1. Elk1 plays a novel role in controlling cell migration. Elk-1 is involved in a number of important cell processes through the activation of different genes in a number of normal tissues as well as in many malignancies. It is also plays a role in breast neoplasia. |
Physical form【外形】 | Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous glycerol solution |
species reactivity | human, mouse, rat |
technique(s) | western blot (chemiluminescent): 1:1,000 using Elk-1 fusion protein phosphorylated with purified Erk2 |
UniProt accession no.【UniProt登记号】 | P19419 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ELK1(2002) mouse ... Elk1(13712) rat ... Elk1(314436) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |