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Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
| 产品编号： | 4063163 |
| 规格： | average Mn (1,600-1,500-1,600), lactide:glycolide 75:25 |
| 包装规格： | 1 G |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
PLGA-PEG-PLGA
结构式
基本信息
| Linear Formula【线性分子式】 | H((C3H4O2)x(C2H2O2)y)m((C2H4O)z)nO((C3H4O2)x(C2H2O2)y)mH |
| Application【应用】 | PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Also this polymer exhibits thermogelation behavior. When applied in biomedical applications, the temperature responsive nature of the copolymer can be tuned to induce an in situ gelation at physiological temperature to provide controlled drug release. These materials have been explored for biomedical applications as temperature-responsive biodegradable systems for drug delivery, tissue engineering and wound healing. |
产品性质
| form【形式】 | semisolid |
| feed ratio【投料比】 | lactide:glycolide 75:25 |
| mol wt【分子量】 | PEG average Mn 1,500 (by NMR) PLGA average Mn 3,200 (by NMR) average Mn (1,600-1,500-1,600) |
| color【颜色】 | white to tan |
| PDI | ≤2.0 <1.1 (Typical PEG PDI ) |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | nwg |
