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α1-Antichymotrypsin 来源于人类血浆

α1-Antichymotrypsin from human plasma
产品编号:4062992
规格:≥92.5% (SDS-PAGE), lyophilized powder
CAS NO:141176-92-3
包装规格:0.1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40629920.1 MG2410
产品别名

141176-92-3

α1-Antichymotrypsin 来源于人类血浆

α1-Antichymotrypsin from human plasma

基本信息
MDL number
MFCD00162030
General description【一般描述】
α1-Antichymotrypsin (α1-ACT) is also known as serpin peptidase inhibitor, clade A member 3 (SERPINA3). It is a 68 kDa serine protease inhibitor, secreted by the liver. It belongs to the serpin superfamily of protease inhibitors. SERPINA3 is located on human chromosome 14q32.1.
Application【应用】
α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.
Biochem/physiol Actions【生化/生理作用】
α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).
Specific inhibitor of chymotrypsin-like serine proteases. Promotes amyloid-β polymerization in vitro and in vivo. Levels in plasma and cerebrospinal fluid have been found to correlate with progression of dementia in Alzheimer′s patients and induce phosphorylation of tau protein in neurons.
Physical form【外形】
Lyophilized powder containing Tris buffer salt and NaCl.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
human plasma
Assay【测定】
≥92.5% (SDS-PAGE)
form【形式】
lyophilized powder
mol wt【分子量】
55-66 kDa
technique(s)
microbiological culture: suitable
UniProt accession no.【UniProt登记号】
P01011
storage temp.【储存温度】
−20℃
Gene Information
human ... SERPINA3(12)
packaging【包装】
Package size based on protein content.
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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