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Lactosyl Ceramide, Bovine-CAS 4682-48-8-Calbiochem
产品别名
4682-48-8
Lactosyl Ceramide, Bovine-CAS 4682-48-8-Calbiochem
LC, Galβ,1,4Glc-Cer, LacCer
Galβ,1,4Glc-Cer, LacCer, LC
基本信息
| Empirical Formula【经验(实验)分子式】 | C53H101NO13 |
| Molecular weight | 960.37 |
| MDL number | MFCD00133445 |
| General description【一般描述】 | A neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fos expression in human aortic smooth muscle cells. Molecular weight: 960.4 (based on tricosanyl -23:0) A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells. M.W. 960.4 (based on tricosanoyl - 23:0). |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Primary Target A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL Cell permeable: no |
| Warning【警告】 | Toxicity: Irritant (B) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C. |
| Other Notes【其他说明】 | Bhunia, A.K., et al. 1997. J. Biol. Chem.272, 15642. Bhunia, A.K., et al. 1996. J. Biol. Chem.271, 10660. Zacharias, C., et al. 1994. J. Biol. Chem.269, 13313. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (TLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze |
| color【颜色】 | colorless |
| solubility【溶解性】 | ethanol: 1 mM methanol: 1 mM |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1 |
| InChI key | VOZHMDQUIRUFQW-AIRKALMMSA-N |
| packaging【包装】 | 1 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
