Serine/Threonine Kinase Inhibitor Set-Calbiochem

100

solid

Calbiochem^®

OK to freeze
desiccated (hygroscopic)
protect from light

DMSO: 1 mg/mL (all other inhibitors)
water: 1 mg/mL (Protein Kinase G Inhibitor)

ambient

−20℃

1 set in Glass bottle

A convenient set that offers several highly selective serine/threonine kinase inhibitors. Kinases play an important role in numerous signaling cascades. Highly selective protein kinase inhibitors are useful for dissecting these cascades to determine which specific kinases are involved in producing particular biological effects. The Serine/Threonine Kinase Inhibitor Set contains the following highly selective serine/ threonine kinase inhibitors in one convenient set:



• Bisindolylmaleimide I (Cat. No. 203290), 250 µg

• H-89, Dihydrochloride (Cat. No. 371963), 1 mg

• KN-93 (Cat. No. 422708), 1 mg

• ML-7 (Cat. No. 475880), 1 mg

• Protein Kinase G Inhibitor (Cat. No. 370654), 1 mg

• Staurosporine (Cat. No. 569397), 100 µg

Cell permeable: yes
Secondary Target
PKC, MLCK, Cam kinase II, PKG
Primary Target
PKA

Toxicity: Multiple Toxicity Values, refer to MSDS (O)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.

Martiny, G., et al. 1993. J. Biol. Chem.268, 9194.
Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.
Chijiwa, T., et al. 1990. J. Biol. Chem.265, 5267.
Simu, M., et al. 1991. Biochem. Biophys. Res. Commun.181, 968.
Saitoh, M., et al. J. Biol. Chem.262, 7796.
Glass, D.B., et al. 1983. Biochem. J.213, 159.
Seynaeve, C.M., et al. 1994. Mol. Pharmacol.45, 1207.
Meyer, T., et al. 1989. Int. J. Cancer43, 851.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany