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Chromeceptin
产品别名
331859-86-0
Chromeceptin
2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene
94G6
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C19H16F3N3O |
Molecular weight | 359.35 |
MDL number | MFCD00815850 |
PubChem Substance ID【PubChem化学物质编号】 | 24724431 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals. |
Features and Benefits【特点和优势】 | This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
color【颜色】 | yellow to brown |
solubility【溶解性】 | H2O: <2 mg/mL DMSO: >20 mg/mL |
storage temp.【储存温度】 | −20℃ |
SMILES string | CN(C)c1ccc2C(c3cccc(c3)C(F)(F)F)C(C#N)=C(N)Oc2c1 |
InChI | 1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3 |
InChI key | GVINXTXGDDSXFQ-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |