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CHR-6494 trifluoroacetate salt
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3425653 | 5 MG | 1310 |
产品别名
1333377-65-3
CHR-6494 trifluoroacetate salt
CHR 6494 trifluoroacetate salt
3-(1H-Indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine trifluoroacetate salt
3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine trifluoroacetate salt
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C16H16N6 · CF3COOH |
Molecular weight | 406.36 |
MDL number | MFCD24849399 |
PubChem Substance ID【PubChem化学物质编号】 | 329825574 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. CHR-6494 causes cell cycle arrest in G2/M and subsequent apoptosis. CHR-6494 causes an abnormal duplication of centrosomes and mitotic catastrophe in cancer cells. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | OC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1 |
InChI | 1S/C16H16N6.C2HF3O2/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13;3-2(4,5)1(6)7/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20);(H,6,7) |
InChI key | ILWYDZNXJQESDI-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |