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1,8-Dihydroxy-3-methylanthraquinone

产品编号:3412510
规格:98%
CAS NO:481-74-3
包装规格:50 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
341251050 MG873
34125101 G6140
产品别名

481-74-3

1,8-Dihydroxy-3-methylanthraquinone

Chrysophanic Acid

3-Methylchrysazin

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H10O4
Molecular weight
254.24
Beilstein
1252300
EC number【EC 号】
207-572-2
MDL number
MFCD00001208
PubChem Substance ID【PubChem化学物质编号】
57648009
NACRES
NA.85
Application【应用】
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .
Biochem/physiol Actions【生化/生理作用】
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .
Other Notes【其他说明】
Keep container tightly closed in a dry and well-ventilated place.
产品性质
Quality Level【质量水平】
100
Assay【测定】
98%
form【形式】
crystalline
color【颜色】
yellow-orange
solubility【溶解性】
chloroform: 1%
Mode of action【作用机制】
enzyme | inhibits
antibiotic activity spectrum【抗生素抗菌谱】
neoplastics
viruses
SMILES string
Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI
1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
InChI key
LQGUBLBATBMXHT-UHFFFAOYSA-N
Gene Information
human ... ELA2(1991)
packaging【包装】
50 mg in glass insert
1 g in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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