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1,8-Dihydroxy-3-methylanthraquinone
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3412510 | 50 MG | 873 | |||
3412510 | 1 G | 6140 |
产品别名
481-74-3
1,8-Dihydroxy-3-methylanthraquinone
Chrysophanic Acid
3-Methylchrysazin
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C15H10O4 |
Molecular weight | 254.24 |
Beilstein | 1252300 |
EC number【EC 号】 | 207-572-2 |
MDL number | MFCD00001208 |
PubChem Substance ID【PubChem化学物质编号】 | 57648009 |
NACRES | NA.85 |
Application【应用】 | Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro . |
Biochem/physiol Actions【生化/生理作用】 | Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus . |
Other Notes【其他说明】 | Keep container tightly closed in a dry and well-ventilated place. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | 98% |
form【形式】 | crystalline |
color【颜色】 | yellow-orange |
solubility【溶解性】 | chloroform: 1% |
Mode of action【作用机制】 | enzyme | inhibits |
antibiotic activity spectrum【抗生素抗菌谱】 | neoplastics viruses |
SMILES string | Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 |
InChI | 1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3 |
InChI key | LQGUBLBATBMXHT-UHFFFAOYSA-N |
Gene Information | human ... ELA2(1991) |
packaging【包装】 | 50 mg in glass insert 1 g in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H315 - H319 - H335 |
Precautionary Statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
Target Organs【靶器官】 | Respiratory system |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |