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BC8-15
产品别名
950385-77-0
BC8-15
3-[(3-Ethyl-1,2,4-triazolo[4,3-c]quinazolin-5-yl)amino]-benzoic acid
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H15N5O2 |
Molecular weight | 333.34 |
PubChem Substance ID【PubChem化学物质编号】 | 329825474 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | BC8-15 is a potent PDE4/8 inhibitor that elevates steroidogenesis in mouse Leydig cells. BC8-15 has the ability to block PDE8A (phosphodiesterase 8A) and PDE4A (phosphodiesterase 4A) with IC50 values of 280 and 220 nM. It helps to increase the synthesis of the steroid from both primary Leydig cells and MA-10 cells. |
Features and Benefits【特点和优势】 | This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 20 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CCC1=NN=C2N1C(NC3=CC=CC(C(O)=O)=C3)=NC4=CC=CC=C42 |
InChI | 1S/C18H15N5O2/c1-2-15-21-22-16-13-8-3-4-9-14(13)20-18(23(15)16)19-12-7-5-6-11(10-12)17(24)25/h3-10H,2H2,1H3,(H,19,20)(H,24,25) |
InChI key | INDKHRIZOIEPIG-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |