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硫唑嘌呤

Azathioprine
产品编号:3411202
规格:Pharmaceutical Secondary Standard; Certified Reference Material
CAS NO:446-86-6
包装规格:1 G
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
34112021 G983
产品别名

446-86-6

硫唑嘌呤

Azathioprine

6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine

6-[(1-Methyl-4-nitro-1H imidazol-5yl) sulfanyl]-7H-purine

6-[(1-甲基-4-硝基-1H-咪唑-5-基)硫代]-1H-嘌呤

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C9H7N7O2S
Molecular weight
277.26
EC number【EC 号】
207-175-4
MDL number
MFCD00069203
PubChem Substance ID【PubChem化学物质编号】
329823278
NACRES
NA.24
General description【一般描述】
Azathioprine is a potentially useful antileukaemic drug, with immunosuppressive action, which is administered orally or by I.V route. It is widely used to treat a variety of auto-immune disorders and also has a marked effect on T-lymphocytes and suppresses cell mediated immunity.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application【应用】
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Azathioprine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using 1H NMR spectroscopy and spectrophotometric techniques.
Analysis Note【分析说明】
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes【其他说明】
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote【附注】
To see an example of a Certificate of Analysis for this material enter LRAA0017 in the slot below. This is an example certificate only and may not be the lot that you receive.
产品性质
Quality Level【质量水平】
300
grade【等级】
certified reference material
pharmaceutical secondary standard
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format【格式】
neat
pharmacopeia traceability【药典可追溯性】
traceable to BP 26
traceable to PhEur A1500000
traceable to USP 1046001
storage temp.【储存温度】
2-30℃
SMILES string
Cn1cnc(c1Sc2ncnc3[nH]cnc23)[N+]([O-])=O
InChI
1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)
InChI key
LMEKQMALGUDUQG-UHFFFAOYSA-N
Gene Information
human ... PPAT(5471)
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H302 - H315 - H319 - H335 - H350
Precautionary Statements
P201 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
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