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亚细亚酸
Asiatic Acid
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3410387 | 10 MG | 3220 | |||
3410387 | 50 MG | 9160 |
产品别名
464-92-6
亚细亚酸
Asiatic Acid
Dammarolic acid
2α,23-Dihydroxyursolic acid
NSC 166063
达玛醇酸
2α, 23-二羟基熊果酸
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C30H48O5 |
Molecular weight | 488.70 |
EC number【EC 号】 | 482-720-9 |
MDL number | MFCD00238541 |
PubChem Substance ID【PubChem化学物质编号】 | 329770790 |
NACRES | NA.25 |
General description【一般描述】 | Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica. |
Application【应用】 | 积雪草酸衍生物合成的起始物料:
Asiatic acid has been used in the in vitro study of its cytotoxic potential in glioblastoma cells. It has also been used for the in vivo quantitative analysis of asiatic acid in Centella asiatica L. and in vitro study of enhancement of asiatic acid yield upon using organic elicitors. |
Biochem/physiol Actions【生化/生理作用】 | Asiatic acid has been reported to exhibit a pernicious effect on glioblastoma, breast, liver, melanoma, and colon cancers and anti-angiogenic activity. Additionally, it can cross the blood-brain barrier and cause apoptosis in human malignant glioma and hepatoma cells. Asiatic acid also effectively inhibits the Ultraviolet A modulated signal transduction pathways and thereby can be used against UVA-induced photoaging of the skin. It has been noted to show antinociceptive and anti-inflammatory properties plus inhibitory effect on neurotoxicity induced by β-amyloid and glutamate. 积雪草酸常用于伤口愈合。积雪草酸具有抗氧化、抗炎和神经保护属性 |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | Centella asiatica |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
storage condition【储存条件】 | protect from light |
color【颜色】 | white |
mp | 325-330 ℃ (lit.) |
solubility【溶解性】 | methanol: 1 mg/mL, clear, colorless |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |
InChI | 1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1 |
InChI key | JXSVIVRDWWRQRT-UYDOISQJSA-N |
packaging【包装】 | 10 mg in glass bottle 50 mg in poly bottle |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |