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亚细亚酸

Asiatic Acid
产品编号:3410387
规格:≥98% (HPLC), from Centella asiatica
CAS NO:464-92-6
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
341038710 MG3220
341038750 MG9160
产品别名

464-92-6

亚细亚酸

Asiatic Acid

Dammarolic acid

2α,23-Dihydroxyursolic acid

NSC 166063

达玛醇酸

2α, 23-二羟基熊果酸

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C30H48O5
Molecular weight
488.70
EC number【EC 号】
482-720-9
MDL number
MFCD00238541
PubChem Substance ID【PubChem化学物质编号】
329770790
NACRES
NA.25
General description【一般描述】
Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.
Application【应用】
积雪草酸衍生物合成的起始物料:
  • 抗癌药
  • 糖原磷酸化酶抑制剂
  • 肝保护剂

Asiatic acid has been used in the in vitro study of its cytotoxic potential in glioblastoma cells. It has also been used for the in vivo quantitative analysis of asiatic acid in Centella asiatica L. and in vitro study of enhancement of asiatic acid yield upon using organic elicitors.
Biochem/physiol Actions【生化/生理作用】
Asiatic acid has been reported to exhibit a pernicious effect on glioblastoma, breast, liver, melanoma, and colon cancers and anti-angiogenic activity. Additionally, it can cross the blood-brain barrier and cause apoptosis in human malignant glioma and hepatoma cells. Asiatic acid also effectively inhibits the Ultraviolet A modulated signal transduction pathways and thereby can be used against UVA-induced photoaging of the skin. It has been noted to show antinociceptive and anti-inflammatory properties plus inhibitory effect on neurotoxicity induced by β-amyloid and glutamate.
积雪草酸常用于伤口愈合。积雪草酸具有抗氧化、抗炎和神经保护属性
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
Centella asiatica
Assay【测定】
≥98% (HPLC)
form【形式】
powder
storage condition【储存条件】
protect from light
color【颜色】
white
mp
325-330 ℃ (lit.)
solubility【溶解性】
methanol: 1 mg/mL, clear, colorless
storage temp.【储存温度】
2-8℃
SMILES string
C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
InChI
1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1
InChI key
JXSVIVRDWWRQRT-UYDOISQJSA-N
packaging【包装】
10 mg in glass bottle
50 mg in poly bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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