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Arctiin
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3410137 | 1 MG | 2920 |
产品别名
20362-31-6
Arctiin
Arctigenin 4-glucoside
Arctigenin-4-glucoside
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C27H34O11 |
Molecular weight | 534.55 |
MDL number | MFCD00870630 |
PubChem Substance ID【PubChem化学物质编号】 | 329824756 |
NACRES | NA.25 |
General description【一般描述】 | Natural product derived from plant source, such as Forsythiae Fructus and Arctium lappa L. Arctiin is a lignan. |
Biochem/physiol Actions【生化/生理作用】 | Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used along or in combination with oseltamivir. Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used alone or in combination with oseltamivir. Arctiin plays an important role in the process of inflammation, by preventing the release of nitric oxide, prostaglandin E2, TNF-α (tumor necrosis factor − α), interleukin (IL)-1β and IL-6. A study using rat model shows that arctiin possess anti-diabetic activity and might serve as an inhibitor of diabetic retinopathy. |
产品性质
Assay【测定】 | ≥95% (LC/MS-ELSD) |
form【形式】 | solid |
storage temp.【储存温度】 | −20℃ |
SMILES string | COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)cc1OC |
InChI | 1S/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1 |
InChI key | XOJVHLIYNSOZOO-SWOBOCGESA-N |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |