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Arctiin

产品编号:3410137
规格:≥95% (LC/MS-ELSD)
CAS NO:20362-31-6
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
34101371 MG2920
产品别名

20362-31-6

Arctiin

Arctigenin 4-glucoside

Arctigenin-4-glucoside

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C27H34O11
Molecular weight
534.55
MDL number
MFCD00870630
PubChem Substance ID【PubChem化学物质编号】
329824756
NACRES
NA.25
General description【一般描述】
Natural product derived from plant source, such as Forsythiae Fructus and Arctium lappa L. Arctiin is a lignan.
Biochem/physiol Actions【生化/生理作用】
Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used along or in combination with oseltamivir.
Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used alone or in combination with oseltamivir. Arctiin plays an important role in the process of inflammation, by preventing the release of nitric oxide, prostaglandin E2, TNF-α (tumor necrosis factor − α), interleukin (IL)-1β and IL-6. A study using rat model shows that arctiin possess anti-diabetic activity and might serve as an inhibitor of diabetic retinopathy.
产品性质
Assay【测定】
≥95% (LC/MS-ELSD)
form【形式】
solid
storage temp.【储存温度】
−20℃
SMILES string
COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)cc1OC
InChI
1S/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1
InChI key
XOJVHLIYNSOZOO-SWOBOCGESA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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