Anti-ZNF322A (AB2) antibody produced in rabbit

NA.41

ZNF322A is a zinc finger transcription factor that is involved in MAPK signaling. Studies have reported that ZNF322A gene is amplified in patients with pulmonary cancers.
Rabbit Anti-ZNF322A antibody recognizes bovine, canine, and human ZNF322A.

Synthetic peptide directed towards the C terminal region of human ZNF322A

Rabbit Anti-ZNF322A antibody is suitable for western blot applications at a concentration of 0.5 μg/ml and for IHC applications at 4-8 μg/ml.

ZNF322 contains four exons and spans 23.2kb in chromosome 6p22.1 region, and transcribes a 2.7kb mRNA that encodes a protein with 402 amino acid residues.Through northern blot analysis, ZNF322 was shown to be expressed in every human tissue examined at adult stage and during embryonic developmental stages from 80 days to 24 weeks. When ZNF322 was overexpressed in COS-7 cells, ZNF322-EGFP fusion protein is detected in the nucleus and cytoplasm. Reporter gene assays show that ZNF322 is a transcriptional activator. Furthermore, overexpression of ZNF322 in COS-7 cells activates the transcriptional activity of SRE and AP-1. Together, these results suggest that ZNF322 is a member of the zinc-finger transcription factor family and may act as a positive regulator in gene transcription mediated by the MAPK signaling pathways.

Synthetic peptide located within the following region: YTVCDKSFHQSSALLQHQTVHIGEKPFVCNVSEKGLELSPPHASEASQMS

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

47 kDa

horse, dog, human

0.5 mg - 1 mg/mL

immunohistochemistry: suitable
western blot: suitable

NP_078915

Q6U7Q0

wet ice

−20℃

human ... ZNF322A(79692)

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12 - Non Combustible Liquids

WGK 2