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Anti-ZNF282 (AB1) antibody produced in rabbit
产品别名
Anti-ZNF282 (AB1) antibody produced in rabbit
Anti-Zinc finger protein 282
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Zinc finger protein 282/ubiquitin-like protein modifier (ZNF282, HUB1), a ubiquitin-like protein, promotes alternative splicing of SRC1 pre-mRNA. HUB1 is essential for subcellular targeting of Snu66, a component of the U4/U6.U5 tri-snRNP splicing complex. |
| Specificity【特异性】 | Anti-ZNF282 (AB1) polyclonal antibody reacts with canine, bovine, human, mouse, and rat zinc finger protein 282/ubiquitin-like protein modifier proteins. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human ZNF282 |
| Application【应用】 | Anti-ZNF282 (AB1) polyclonal antibody is used to tag zinc finger protein 282/ubiquitin-like protein modifier for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of zinc finger protein 282/ubiquitin-like protein modifier in the regulation of pre-mRNA splicing. |
| Biochem/physiol Actions【生化/生理作用】 | ZNF282 contains 1 KRAB domain and 5 C2H2-type zinc fingers. It belongs to the krueppel C2H2-type zinc-finger protein family and binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. |
| Sequence【序列】 | Synthetic peptide located within the following region: QQLGIQGLGLDSGSWSWAQALPPEEVCHQEPALRGEMAEGMPPMQAQEWD |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 74 kDa |
| species reactivity | rabbit, human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_003566 |
| UniProt accession no.【UniProt登记号】 | Q9UDV7 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ZNF282(8427) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
