Anti-ZNF265 antibody produced in rabbit

NA.41

Synthetic peptide directed towards the N terminal region of human ZNF265

ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.

Synthetic peptide located within the following region: RCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARR

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

37 kDa

rabbit, bovine, dog, human, horse, mouse, guinea pig, rat

0.5 mg - 1 mg/mL

western blot: suitable

NP_005446

Q5VV34

wet ice

−20℃

human ... ZNF265(9406)

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12 - Non Combustible Liquids

WGK 1