您的位置：首页 > 产品中心 > Anti-WSTF (N-Terminal) antibody produced in rabbit
Anti-WSTF (N-Terminal) antibody produced in rabbit
| 产品编号： | 3405902 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-WSTF (N-Terminal) antibody produced in rabbit
Anti-Bromdomain Adjacent to Zn Finger Domain 1B
Anti-Williams-Beuren Syndrome Chromosome Region 9
Anti-Williams Syndrome Transcription Factor
Anti-BAZ1B
基本信息
| MDL number | MFCD08705536 |
| NACRES | NA.41 |
| General description【一般描述】 | The gene encoding Williams syndrome transcription factor (WSTF)/bromodomain adjacent to zinc finger domain 1B (BAZ1B), contains 20 exons extended over a length of 80kb on genomic DNA. The gene is localized on human chromosome 7q11.23. The encoded protein is composed of 1425 amino acids and is widely expressed in both adult and fetal tissues. WSTF contains one PHD-type zinc finger motif and a bromo domain. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 2-20 of human WSTF, conjugated to KLH via a C-terminal added cysteine residue. The sequence is conserved in human, mouse, and rat. |
| Application【应用】 | Anti-WSTF (N-Terminal) antibody produced in rabbit has been used in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). |
| Biochem/physiol Actions【生化/生理作用】 | Williams syndrome transcription factor (WSTF) acts as a key component of WICH (WSTF-ISWI chromatin remodeling complex) and the WINAC (WSTF including the nucleosome assembly complex). WICH and WINAC complexes plays a vital role in replication of heterochromatin and vitamin D-mediated transcription and replication, respectively. In addition, WSTF is also involved in neurodevelopment. Hemizygous deletion of the gene leads to a neurodevelopmental disorder, Williams syndrome (WS). |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 175 kDa |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): 5-10 μg using from lysates of HEK293-T cells western blot: 0.5-1 μg/mL using extracts of MCF-7 breast cancer cell line |
| UniProt accession no.【UniProt登记号】 | Q9UIG0 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BAZ1B(9031) mouse ... Baz1b(22385) rat ... Baz1b(368002) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
