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Anti-WSTF (C-Terminal) antibody produced in rabbit
| 产品编号： | 3405901 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-WSTF (C-Terminal) antibody produced in rabbit
Anti-Bromdomain Adjacent to Zn Finger Domain 1B
Anti-Williams-Beuren Syndrome Chromosome Region 9
Anti-Williams Syndrome Transcription Factor
Anti-BAZ1B
基本信息
| MDL number | MFCD08705535 |
| NACRES | NA.41 |
| General description【一般描述】 | Williams syndrome transcription factor (WSTF) belongs to the WAL/BAZ/WAC protein family, encoded by the bromodomain adjacent to zinc finger domain 1B (BAZ1B) gene. It is a non-secretory protein, which consists of a C-terminal bromodomain adjacent to a PHD (plant homeodomain) finger. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 1467-1483 of human WSTF, conjugated to KLH via an N-terminal added cysteine residue. The corresponding rat and mouse sequence differ from the immunizing sequence by three amino acids. |
| Application【应用】 | Anti-WSTF (C-Terminal) antibody produced in rabbit has been used in western blotting and immunofluorescence. Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Biochem/physiol Actions【生化/生理作用】 | Williams syndrome transcription factor (WSTF) is implicated in transcription, replication, chromatin remodeling and DNA damage response. It acts as a tyrosine protein kinase. Mutations in this gene are associated with Williams-Beuren syndrome. WSTF might function as an activator of gene expression of cytochrome P450 family 21 subfamily A member 2 (CYP21A2) and CYP19A1. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 175 kDa |
| species reactivity | human, mouse |
| technique(s) | immunoprecipitation (IP): 5-10 μg using from lysates of HEK293-T cells indirect immunofluorescence: 10-20 μg/mL using paraformaldehyde-fixed NIH3T3 cells microarray: suitable western blot: 0.5-1 μg/mL using extracts of MCF-7 breast cancer cell line |
| UniProt accession no.【UniProt登记号】 | Q9UIG0 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BAZ1B(9031) mouse ... Baz1b(22385) rat ... Baz1b(368002) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
