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Anti-VMAT2 antibody produced in rabbit
产品编号: | 3405085 |
规格: | ~1 mg/mL, affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-VMAT2 antibody produced in rabbit
Anti-SLC18A2
Anti-SVAT
Anti-Solute carrier family 18 (vesicular monoamine), member 2
Anti-SVMT
Anti-VAT2
Anti-VMAT2
基本信息
MDL number | MFCD02097601 |
NACRES | NA.41 |
General description【一般描述】 | Vesicular monoamine transporter 2 (VMAT2) , also known as solute carrier family 18 member A2 (SLC18A2), is a transmembrane protein that acts at nerve terminals. It is expressed in platelets and in central, peripheral and enteric neurons. The gene encoding VMAT2 consists of 16 exons and is mapped to human chromosome 10q25. |
Immunogen【免疫原】 | synthetic peptide corresponding an internal sequence of human VMAT2. This sequence is identical in mouse and rat. |
Application【应用】 | Anti-VMAT2 antibody produced in rabbit has been used in western blot analysis. Anti-VMAT2 antibody produced in rabbit has also been used in immunofluorescence. |
Biochem/physiol Actions【生化/生理作用】 | Vesicular monoamine transporter 2 (VMAT2) modulates the release of neurotransmitters like dopamine, serotonin and γ-amino butyric acid. It has a role in the accumulation of neurotransmitters in synaptic vesicles to prevent toxicity. VMAT2 has been linked to tardive dyskinesia and may be associated with Parkinson′s disease. |
Physical form【外形】 | solution in phosphate buffered saline, containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | rat, mouse, human |
concentration【浓度】 | ~1 mg/mL |
technique(s) | immunohistochemistry: 1:100-1:250 western blot: 1:500-1:1,000 |
UniProt accession no.【UniProt登记号】 | Q05940 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... SLC18A2(6571) mouse ... Slc18a2(214084) rat ... Slc18a2(25549) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |