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Anti-USP28 antibody produced in mouse
| 产品编号： | 3404615 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-USP28 antibody produced in mouse
KIAA1515
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Ubiquitin specific peptidase 28 (USP28) belongs to ubiquitin-specific protease family. It is highly expressed in heart and muscles. It is homologous to ubiquitin specific peptidase (USP25).USP28 gene is located on human chromosome 11q23.2. |
| Immunogen【免疫原】 | USP28 (AAH65928.1, 1 a.a. ~ 583 a.a) full-length human protein. Sequence MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALKASNGDITQAVSLLTDERVKEPSQDTVATEPSEVEGSAANKEVLAKVIDLTHDNKDDLQAAIALSLLESPKIQADGRDLNRMHEATSAETKRSKRKRCEVWGENPNPNDWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDHSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKEEIKILQQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSSVHCSVSDQTSKESTSTESSSQDVESTFSSPEDSLPKSKPLTSSRSSMEMPSQPAPRTVTDEEINFVKTCLQRWRSEIEQDIQDLKTCIASTTQTIEQMYCDPLLRQVE |
| Application【应用】 | Anti-USP28 antibody produced in mouse has been used in immunohistochemistry and western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | Ubiquitin specific peptidase 28 (USP28) is a deubiquitinating enzyme, which is involved in DNA damage pathway. Downregulation of USP28 causes cell apoptosis and upregulation induces non-small cell lung cancer (NSCLC). USP28 is used as a target of therapy for human malignant glioma, as it contributes to glioma tumorigenicity. USP28 protein expression is used as a prognostic marker for bladder cancer. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~66.2 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 | BC065928.1 |
| UniProt accession no.【UniProt登记号】 | Q96RU2 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... USP28(57646) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
