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Anti-TRAP antibody produced in rabbit
基本信息
NACRES | NA.41 |
General description【一般描述】 | Tartrate-resistant acid phosphatase type 5 (TRAP/ACP5) gene spans 3 kb on human chromosome 19p13.2. TRAP enzyme is a member of acid phosphatase family that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is widely expressed in human liver and osteoclasts. |
Immunogen【免疫原】 | Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human TRAP. |
Application【应用】 | Anti-TRAP antibody produced in rabbit has been used in western blotting. |
Biochem/physiol Actions【生化/生理作用】 | Tartrate-resistant acid phosphatase type 5 (TRAP/ACP5) is an iron binding protein that plays a crucial role in the bone resorption process. Decreased expression of the gene has been observed in hepatocellular carcinoma (HCC) patients. Genetic variations of the gene leads to the development of immuno-osseous disorder spondyloenchondrodysplasia, systemic lupus erythematosus (SLE) and a type I interferon (IFN) signature. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500943. |
Physical form【外形】 | Supplied at 1 mg/mL in PBS with 0.02% sodim azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | mouse, human |
concentration【浓度】 | 1 mg/mL |
technique(s) | ELISA: suitable immunoblotting: suitable immunofluorescence: suitable |
NCBI accession no.【NCBI登记号】 | NP_001104505 |
UniProt accession no.【UniProt登记号】 | P13686 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |