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Anti-TGFBI antibody produced in rabbit
产品别名
Anti-TGFBI antibody produced in rabbit
Anti-CDGG1
Anti-CSD2
Anti-BIGH3
Anti-CSD1
Anti-CDB1
Anti-Transforming growth factor, β-induced, 68 kDa
Anti-CSD
Anti-CDG2
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 46 kDa |
species reactivity | guinea pig, rabbit, human, bovine, horse, mouse |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | immunofluorescence: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_000349 |
UniProt accession no.【UniProt登记号】 | Q15582 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TGFBI(7045) |
基本信息
General description【一般描述】 | Transforming growth factor, β-induced, 68 kDa (TGFB1, BIGH3, CDB1, CDG2, CDGG1, CSD) is a cell signaling protein with a wide range of functions, mostly as a negative/suppressive modulator of cell growth. TGFB1 is a modulator of immune function and an inducer of cell transformation. The actions of TGFB1 are mediated via transforming growth factor β receptors. |
Specificity【特异性】 | Anti-TGFBI polyclonal antibody reacts with chicken, human, mouse, rat, bovine, pig, and rabbit transforming growth factor, β 1 proteins. |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human TGFBI |
Application【应用】 | Anti-TGFBI polyclonal antibody is used to tag transforming growth factor, β 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of transforming growth factor, β 1 in cell signaling within a wide range of cell types. |
Biochem/physiol Actions【生化/生理作用】 | TGFBI Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. |
Sequence【序列】 | Synthetic peptide located within the following region: LKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSA |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |