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Anti-TFE3 antibody produced in rabbit
产品别名
Anti-TFE3 antibody produced in rabbit
Anti-BHLHE33
Anti-RCCP2
Anti-TFEA
基本信息
NACRES | NA.41 |
General description【一般描述】 | The antibody detects endogenous levels of total TFE3 protein. |
Immunogen【免疫原】 | Peptide sequence around aa. 303-307 (L-D-V-Y-S), according to the protein NP_006512.2 |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~70 kDa |
species reactivity | rat, human, mouse |
concentration【浓度】 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (L-D-V-Y-S) |
NCBI accession no.【NCBI登记号】 | NM_006521.4 |
UniProt accession no.【UniProt登记号】 | P19532 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TFE3(7030) |
产品说明
Target description【目标描述】 | Transcription factor that specifically recognizes and binds E-box sequences (3′-CANNTG-5′). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |