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Anti-TET2 antibody produced in rabbit
基本信息
NACRES | NA.41 |
General description【一般描述】 | Tet methylcytosine dioxygenase 2 (TET2) is part of the Fe(II)/α-ketoglutarate-dependent dioxygenase family of enzymes. It is expressed in the brain. The gene encoding TET2 is localized on human chromosome 4q24. |
Immunogen【免疫原】 | Antibody was raised against an 18 amino acid peptide near the amino terminus of human TET2. |
Application【应用】 | Anti-TET2 antibody produced in rabbit has been used in Western blotting. |
Biochem/physiol Actions【生化/生理作用】 | Tet methylcytosine dioxygenase 2 (TET2) is involved in the conversion of 5-methylcytosine to 5-hydroxymethyl-cytosine (5hmC). It also has a role in stimulating DNA demethylation and lymphomagenesis. Mutations in the gene encoding TET2 have been linked to myelodysplastic syndromes. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500711. |
Physical form【外形】 | Supplied at 1 mg/mL in PBS with 0.02% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
mol wt【分子量】 | 220 kDa |
species reactivity | human |
concentration【浓度】 | 1 mg/mL |
technique(s) | ELISA: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001120680 |
UniProt accession no.【UniProt登记号】 | Q6N021 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TET2(54790) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |