您的位置：首页 > 产品中心 > Anti-PYCR2 antibody produced in mouse
Anti-PYCR2 antibody produced in mouse
| 产品编号： | 3389780 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PYCR2 antibody produced in mouse
P5CR2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Pyrroline-5-carboxylate reductase 2 (PYCR2) gene is located on human chromosome 1q42.12. PYCR2 is expressed mainly in dermal fibroblasts. |
| Immunogen【免疫原】 | PYCR2 (NP_037460.2, 1 a.a. ~ 320 a.a) full-length human protein. Sequence MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLTPSSPGKLLTRSLALGGKKD |
| Biochem/physiol Actions【生化/生理作用】 | Pyrroline-5-carboxylate reductase 2 (PYCR2) encodes an enzyme involved in proline synthesis in mitochondria. It converts pyrroline-5-carboxylate to proline. PYCR2 mutations is linked to microcephaly, craniofacial dysmorphism, progressive psychomotor disability, hyperkinetic movements and axial hypotonia with variable appendicular spasticity. PYCR2 is a therapeutic target of melanoma. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~33.6 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 | NM_013328.2 |
| UniProt accession no.【UniProt登记号】 | Q96C36 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PYCR2(29920) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
