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Anti-PXN (Ab-88) antibody produced in rabbit
产品别名
Anti-PXN (Ab-88) antibody produced in rabbit
Anti-Paxillin antibody produced in rabbit
Anti-FLJ16691 antibody produced in rabbit
基本信息
NACRES | NA.41 |
General description【一般描述】 | PXN (paxillin) is a focal adhesion-associated tyrosine-based protein, that is present in the cytoplasm. It is a 68kDa protein that is located on chromosome 12q24. |
Immunogen【免疫原】 | Peptide sequence around aa. 86-90 (P-V-Y-G-S), according to the protein PXN. |
Application【应用】 | Anti-PXN (Ab-88) antibody has been used in immunofluorescence. |
Biochem/physiol Actions【生化/生理作用】 | Paxillin (PXN) controls signal transduction, cell morphology and motility, cytoskeletal rearrangements, proliferation and apoptosis. It serves as an oncogene, hence it plays a major role in the growth of human carcinomas. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~68 kDa |
species reactivity | human |
concentration【浓度】 | 1 mg/mL |
technique(s) | indirect immunofluorescence: 1:50-1:100 western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (P-V-Y-G-S) |
NCBI accession no.【NCBI登记号】 | NP_001074324.1 |
UniProt accession no.【UniProt登记号】 | P49023 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PXN(5829) |
产品说明
Target description【目标描述】 | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |