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Anti-PTPRC antibody produced in chicken
产品编号: | 3389564 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-PTPRC antibody produced in chicken
Anti-Leukocyte common antigen
Anti-LCA
Anti-CD45
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Immunogen Sequence: GI # 18641347, sequence 482-552 Recombinant protein tyrosine phosphatase, receptor type, C isoform 1 |
Application【应用】 | Anti-PTPRC antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
Biochem/physiol Actions【生化/生理作用】 | Protein tyrosine phosphatase, receptor type, C is an enzyme encoded by the PTPRC gene in humans. It is also known as CD45 antigen (CD stands for cluster of differentiation) and is originally called leukocyte common antigen (LCA). PTPRC acts as a binding receptor for galectin-3 and helps in inducing apoptosis of Jurkat cells. It plays a novel role on innate immune cells in promoting lymphopenia-induced T cell proliferation. The leukocyte-specific tyrosine phosphatase impacts T cell development and activation by modulating TCR signaling. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
manufacturer/tradename | Genway 15-288-21465 |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_002829.2 |
UniProt accession no.【UniProt登记号】 | P08575 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PTPRC(5788) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |