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ANTI-PRKCI antibody produced in mouse

产品编号:3388384
规格:clone 1C10, purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3388384100 μG5040
产品别名

ANTI-PRKCI antibody produced in mouse

PRKCI

DXS1179E

PKCI

MGC26534

nPKC-iota

基本信息
NACRES
NA.41
General description【一般描述】
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. (provided by RefSeq)
Immunogen【免疫原】
PRKCI (AAH22016, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCV
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
1C10, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 36.74 kDa
species reactivity
human
technique(s)
indirect ELISA: suitable
western blot: 1-5 μg/mL
isotype【同位素/亚型】
IgG1κ
NCBI accession no.【NCBI登记号】
BC022016
UniProt accession no.【UniProt登记号】
P41743
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... PRKCI(5584)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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