Anti-Potassium Channel K_V4.1 兔抗

NA.41

peptide (C)KRRAIRLANSTAS, corresponding to residues 538-550 of the human K_v4.1.The epitope is localized intracellularly in C-terminal.

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

lyophilized powder

mouse, rat, human

western blot: 1:400 using human neuroblastoma cell line SH-SY5Y

Q9NSA2

dry ice

−20℃

human ... KCND1(3750)
mouse ... Kcnd1(16506)
rat ... Kcnd1(116695)

The K_v4 channels are characterized by activation at subthreshold membrane potentials, inactivate rapidly and recover from inactivation quickly compared with other voltage-dependent K⁺ channels. This type of current is known as transient A-type K⁺ currents. For example, depolarization-activated K⁺ currents in rat neostriatal cholinergic interneurons are predominantly of the A-type and attributable to coexpression of K_v4.1 and K_v4.2 subunits.

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