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Anti-Potassium Channel KV11.2 (erg2) 兔抗
Anti-Potassium Channel Kv11.2 (erg2) antibody produced in rabbit
产品编号: | 3387473 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 50 μL,200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Potassium Channel KV11.2 (erg2) 兔抗
Anti-Potassium Channel Kv11.2 (erg2) antibody produced in rabbit
Anti-ether-a-go-go-related channel 2
Anti-KCNH6
基本信息
NACRES | NA.41 |
General description【一般描述】 | The gene Kcnh6 (potassium voltage-gated channel subfamily H member 6), also referred to as erg2, encodes a subunit of ether-à-go-go related (erg) K+ channels. The erg K+ channels are part of the EAG (ether-à-go-go) family of voltage-gated K+ channels. The encoded protein is found to be expressed in the rat retina. The three isoforms erg1, erg2, and erg3 are found to be expressed in the brain. They are strongly expressed in the olfactory bulb. |
Immunogen【免疫原】 | peptide TLNFVEFNLEKHRS(C), corresponding to residues 185- 198 of human Kv11.2 located in N-terminal part of human Kv11.2. |
Biochem/physiol Actions【生化/生理作用】 | The gene Kcnh6 (potassium voltage-gated channel subfamily H member 6) encodes a voltage gated K+ channel that modulates the membrane potential in its rested and activated state. It may participate in the tweaking of the presynaptic membrane potential, thereby regulating neurotransmitter release. |
Physical form【外形】 | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide. |
Reconstitution【重悬】 | Reconstitute with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%). |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | rat |
technique(s) | immunohistochemistry: suitable western blot: 1:200 using rat brain and rat cortex lysates |
UniProt accession no.【UniProt登记号】 | O54853 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | rat ... Kcnh6(116745) |
产品说明
Target description【目标描述】 | Potassium Channel KV11.2 (erg2) encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Kv11.2 produces currents characterized by strong inward rectification with slow activation and very rapid inactivation kinetics, which closely resemble those produced by the much studied channel Kv11.1. The expression of Kv11.2 seems to be limited to the brain and the pituitary gland. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |