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Anti-PMF1 antibody produced in rabbit
产品别名
Anti-PMF1 antibody produced in rabbit
Anti-Polyamine-modulated factor 1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Polyamines are transcription factors that regulate cell proliferation and apoptosis. Polyamine modulated factor-1 (PMF-1) interacts with Nrf-2 and subsequently modulates SSAT gene transcription. Methylation of PMF1 has been linked to the progression of bladder cancer. Rabbit Anti-PMF1 antibody recognizes bovine, human, mouse, rat, pig, and canine PMF1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human PMF1 |
| Application【应用】 | Rabbit Anti-PMF1 antibody is suitable for use in western blot applications at a concentration of 2.5μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | PMF1 is part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. It may act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. |
| Sequence【序列】 | Synthetic peptide located within the following region: AAGSYQRFTDCYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGN |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 23 kDa |
| species reactivity | human, goat |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_009152 |
| UniProt accession no.【UniProt登记号】 | Q6P1K2 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PMF1(11243) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
