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Anti-PKR antibody produced in rabbit
产品编号: | 3386579 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-PKR antibody produced in rabbit
Anti-Interferon-inducible RNA-dependent protein kinase
Anti-Protein kinase RNA-activated
基本信息
MDL number | MFCD03455796 |
NACRES | NA.41 |
General description【一般描述】 | EIF2AK2 (eukaryotic translation initiation factor 2 α kinase 2) is an intracellular protein that is also called as RNA-dependent protein kinase (PKR). It belongs to the eIF2α family of protein kinases. The protein contains two RNA binding domains and a kinase domain. The PKR gene is localized on human chromosome 2p22-p21. |
Immunogen【免疫原】 | PKR antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human PKR. |
Application【应用】 | Anti-PKR antibody produced in rabbit has been used in Western Blotting. |
Biochem/physiol Actions【生化/生理作用】 | EIF2AK2 (eukaryotic translation initiation factor 2 α kinase 2) plays a key role in antiviral responses promoted by interferons. It is involved in stress response and inflammation pathways. EIF2AK2 controls the development and multiplication of cells, nutrient signaling and metabolism. The protein also participates in several cell regulatory pathways like antiviral activity, growth suppression, transcriptional regulation and apoptosis. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500326. |
Physical form【外形】 | Supplied in PBS with 0.02% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | rat, mouse, human |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | AAP57628 |
UniProt accession no.【UniProt登记号】 | P19525 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... EIF2AK2(5610) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |