Anti-PKM2 antibody produced in rabbit

NA.41

The antibody detects endogenous levels of total PKM2 protein.

Peptide sequence around aa. 36-40 (D-S-P-P-I), according to the protein NP_872270.1

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~60 kDa

human

1 mg/mL

western blot: 1:500-1:1000

IgG

(D-S-P-P-I)

NM_182470.1

wet ice

−20℃

human ... PKM2(5315)

Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

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10 - Combustible liquids

WGK 1