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Anti-phospho-NTRK2 (pTyr515) antibody produced in rabbit
产品别名
Anti-phospho-NTRK2 (pTyr515) antibody produced in rabbit
Anti-neurotrophic tyrosine kinase, receptor, type 2 antibody produced in rabbit
Anti-TRKB antibody produced in rabbit
Anti-GP145-TrkB antibody produced in rabbit
基本信息
| MDL number | MFCD01092509 |
| NACRES | NA.41 |
| General description【一般描述】 | NTRK2 (neurotrophic tyrosine kinase receptor type 2) is also known as TRKB (tropomyosin receptor kinase B). It belongs to the Trk family of neurotrophin receptors. It is located on chromosome 9q21.32. |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 515 (P-Q-Y(p)-F-G), according to the protein NTRK2. |
| Application【应用】 | Anti-phospho-NTRK2 (pTyr515) antibody has been used in western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | In NB (neuroblastoma), NTRK2 (neurotrophic tyrosine kinase receptor type 2) controls the favorable and unfavorable clinical actions. It also controls the roles of glutamate receptor and synaptic plasticity in the amygdala . |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~140 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (P-Q-Y-PF-G) |
| NCBI accession no.【NCBI登记号】 | NP_001007098.1 |
| UniProt accession no.【UniProt登记号】 | Q16620 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NTRK2(4915) |
产品说明
| Target description【目标描述】 | Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
