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Anti-phospho-NTRK1 (pSer791) antibody produced in rabbit
产品别名
Anti-phospho-NTRK1 (pSer791) antibody produced in rabbit
Anti-MTC antibody produced in rabbit
Anti-neurotrophic tyrosine kinase, receptor, type 1 antibody produced in rabbit
Anti-TRK1 antibody produced in rabbit
Anti-DKFZp781I14186 antibody produced in rabbit
Anti-TRK antibody produced in rabbit
基本信息
| MDL number | MFCD00239748 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine791 (P-V-Y(p)-L-D), according to the protein NTRK1. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~140 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (P-V-YP-L-D) |
| NCBI accession no.【NCBI登记号】 | NP_001007793.1 |
| UniProt accession no.【UniProt登记号】 | P04629 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NTRK1(4914) |
产品说明
| Target description【目标描述】 | Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
