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Anti-phospho-NBN (pSer343) antibody produced in rabbit
产品别名
Anti-phospho-NBN (pSer343) antibody produced in rabbit
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基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G), according to the protein NBN. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~95 kDa |
species reactivity | human |
concentration【浓度】 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (S-L-SP-Q-G) |
NCBI accession no.【NCBI登记号】 | NP_002476.2 |
UniProt accession no.【UniProt登记号】 | O60934 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... NBN(4683) |
产品说明
Target description【目标描述】 | Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |