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Anti-phospho-CD4 (pSer433) antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31. CD4 belongs to the immunoglobulin superfamily (IgSF). It has four extracellular Ig-like domains, a hydrophobic transmembrane region and a 40-residue cytoplasmic tail. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human CD4 around the phosphorylation site of Ser433. Immunogen Range: 401-450 |
| Biochem/physiol Actions【生化/生理作用】 | CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serves as a primary receptor for HIV-1 entry. Individuals with infectious and chronic inflammatory diseases shows higher level of soluble CD4 (sCD4). |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 51 kDa |
| species reactivity | mouse, human, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
| NCBI accession no.【NCBI登记号】 | P01730 |
| UniProt accession no.【UniProt登记号】 | P01730 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CD4(920) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
