Anti-Pael-R (GPR37) (C-term) antibody produced in rabbit

NA.41

Parkinson is the second most common neurodegenerative disease after Alzheimer′s. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.

PAEL-R (NP_005293.1, 222-256)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the C-terminal region of human Pael-R (GPR37).

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

rabbit

200

unconjugated

saturated ammonium sulfate (SAS) precipitated

primary antibodies

polyclonal

buffered aqueous solution

human

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NP_005293.1

dry ice

−20℃

human ... PAEL-R(2861)

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12 - Non Combustible Liquids

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