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Anti-Nestin (C-terminal) antibody produced in rabbit
产品编号: | 3380009 |
规格: | ~1.5 mg/mL, affinity isolated antibody |
包装规格: | 25 μL,200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Nestin (C-terminal) antibody produced in rabbit
Anti-NES
基本信息
NACRES | NA.41 |
General description【一般描述】 | Nestin/NES belongs to the intermediate filament (IF) protein family. Its expression is found in immature neuroepithelial and progenitor cell types. This 240 kDa protein contains the shortest head domain (N-terminus) and a long tail domain (C-terminus). Nestin is mapped to human chromosome 1q23.1. |
Immunogen【免疫原】 | synthetic peptide corresponding to a sequence at the C- terminus of mouse nestin, conjugated to KLH. The sequence is identical in rat nestin. |
Application【应用】 | Anti-Nestin (C-terminal) antibody has been used in immunostaining. |
Biochem/physiol Actions【生化/生理作用】 | Nestin/NES plays a major role in the modulation of assembly and disassembly of intermediate filaments, which in turn help in the remodeling of the cell along with other structural proteins. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~300 kDa |
species reactivity | mouse, rat |
packaging【包装】 | antibody small pack of 25 μL |
enhanced validation【增强验证】 | recombinant expression Learn more about Antibody Enhanced Validation |
concentration【浓度】 | ~1.5 mg/mL |
technique(s) | indirect immunofluorescence: 1-2 μg/mL using mouse P19 cells western blot: 2-4 μg/mL using lysates of HEK293T cells over-expressing rat nestin. |
UniProt accession no.【UniProt登记号】 | P21263 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Nes(18008) rat ... Nes(25491) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |