Anti-MIP-1β antibody produced in chicken

NA.41

MIP-1β (macrophage inflammatory protein 1β) is a member of the CC chemokine (cysteine-cysteine) family, and is produced by monocytes and macrophages. This protein exists as a homodimer. It acts as a ligand to the GPCR (G-protein coupled receptor) called CCR5 (CC chemokine receptor 5).

Recombinant chemokine C-C motif ligand 4 isoform 1
Immunogen Sequence: GI # 4506845, sequence 27-92

Anti-MIP-1β antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Chemokine (C-C motif) ligand 4 (CCL4) is a principal regulator of macrophage migration and signals through CCR5. CCR5 is linked to several protein kinases including the src kinase Lyn, PI3K, focal adhesion related kinase Pyk2 and members of the MAPK family that help in regulating macrophage chemotaxis. CCL4 is released at the site of inflammation in sarcoidosis.

Solution in phosphate buffered saline containing 0.02% sodium azide.

chicken

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human

Genway 15-288-21035

indirect ELISA: suitable
western blot: suitable

NP_002975.1

P13236

wet ice

−20℃

human ... CCL4(6351)

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12 - Non Combustible Liquids

WGK 1

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)