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Anti-KCNN4 antibody produced in rabbit
产品别名
Anti-KCNN4 antibody produced in rabbit
Anti-IKCA1
Anti-hIKCa1
Anti-SK4
Anti-hKCa4
Anti-IK1
Anti-KCA4
Anti-KCa3.1
Anti-Small conductance calcium-activated channel, subfamily N, member 4
基本信息
NACRES | NA.41 |
General description【一般描述】 | Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, KCNN4, is a component of a potassium channel activated by calcium. It is critically involved in calcium ion transport and cell homeostasis. |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human KCNN4 |
Application【应用】 | Anti-KCNN4 antibody produced in rabbit has been used in:
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Biochem/physiol Actions【生化/生理作用】 | KCNN4 (potassium calcium-activated channel subfamily N member 4) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. |
Sequence【序列】 | Synthetic peptide located within the following region: DLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
mol wt【分子量】 | 48 kDa |
species reactivity | human |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_002241 |
UniProt accession no.【UniProt登记号】 | O15554 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... KCNN4(3783) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |