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Anti-JAK2 antibody produced in rabbit
产品别名
Anti-JAK2 antibody produced in rabbit
JAK-2
kinase Jak2
JAK2
Janus kinase 2
基本信息
| MDL number | MFCD00802820 |
| NACRES | NA.41 |
| General description【一般描述】 | JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the the Jak family of proteins. It is located on human chromosome 9p24. Anti-JAK2 antibody detects endogenous levels of total JAK2 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human JAK2. Immunogen Range: 541-590 |
| Biochem/physiol Actions【生化/生理作用】 | JAK2 (janus kinase 2) plays an important role in the activities of cytokines receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 130 kDa |
| species reactivity | mouse, human, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | O60674 |
| UniProt accession no.【UniProt登记号】 | O60674 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... JAK2(3717) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
